Enantiospecific syntheses of the potent bioactives nagilactone F and the mould metabolite LL-Z1271α an evaluation of their allelopathic potential

Improved syntheses are described for nagilactone F and the antibiotic LL-Z1271α, two of the most potent bioactive members of the podolactone family. The allelopathic potential of some members of this podolactone series has been evaluated, with the result that the metabolite LL-Z1271α is one of the m...

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Bibliographic Details
Published in:Tetrahedron 1999-06, Vol.55 (23), p.7289-7304
Main Authors: Barrero, Alejandro F, Sánchez, Juan F, Elmerabet, Jamal, Jiménez-González, David, Macías, Francisco A, Simonet, Ana M
Format: Article
Language:English
Subjects:
herbicides
podolactones
synthesis
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Summary:Improved syntheses are described for nagilactone F and the antibiotic LL-Z1271α, two of the most potent bioactive members of the podolactone family. The allelopathic potential of some members of this podolactone series has been evaluated, with the result that the metabolite LL-Z1271α is one of the most active compounds. Graphic
ISSN:0040-4020
1464-5416
DOI:10.1016/S0040-4020(99)00355-5