Efficient synthesis of benzylic bromides under neutral conditions on solid support

A method of benzylic alcohol bromination on solid phase in neutral conditions was developed. Its application to the preparation of brominated linkers is described.

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Bibliographic Details
Published in:Tetrahedron letters 2000-12, Vol.41 (51), p.9985-9988
Main Authors: Zoller, Thomas, Ducep, Jean-Bernard, Hibert, Marcel
Format: Article
Language:English
Subjects:
bromination
linker
solid phase synthesis
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Description
Summary:A method of benzylic alcohol bromination on solid phase in neutral conditions was developed. Its application to the preparation of brominated linkers is described.
ISSN:0040-4039
1873-3581
DOI:10.1016/S0040-4039(00)01648-8