An efficient method to prepare α-sulfonyl hydroxamic acid derivatives

α-Sulfonyl hydroxamic acid derivatives are biologically important molecules. An efficient protocol has been developed to make these molecules via a direct sulfonylation of enolates. Several piperidine containing α-sulfonyl hydroxamic acid compounds have been prepared by this procedure. Graphic

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Bibliographic Details
Published in:Tetrahedron letters 2001-07, Vol.42 (28), p.4605-4607
Main Authors: Sandanayaka, Vincent P, Zask, Arie, Venkatesan, Aranapakam M, Baker, Jannie
Format: Article
Language:English
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Summary:α-Sulfonyl hydroxamic acid derivatives are biologically important molecules. An efficient protocol has been developed to make these molecules via a direct sulfonylation of enolates. Several piperidine containing α-sulfonyl hydroxamic acid compounds have been prepared by this procedure. Graphic
ISSN:0040-4039
1873-3581
DOI:10.1016/S0040-4039(01)00835-8