One-pot facile conversion of the acetates of Baylis–Hillman adducts into substituted fused pyrimidones in aqueous media

A facile, one-pot convenient transformation of the acetates of Baylis–Hillman adducts into fused pyrimidones, i.e. 3-substituted-1,5-diazabicyclo(4.4.0)deca-2,5,7,9-tetraen-4-ones via reaction with 2-aminopyridine in environmentally friendly aqueous media is described. A facile, one-pot convenient t...

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Bibliographic Details
Published in:Tetrahedron letters 2002-06, Vol.43 (24), p.4301-4303
Main Authors: Basavaiah, Deevi, Satyanarayana, Tummanapalli
Format: Article
Language:English
Subjects:
aqueous media
Baylis–Hillman chemistry
environmentally friendly
fused pyrimidones
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Summary:A facile, one-pot convenient transformation of the acetates of Baylis–Hillman adducts into fused pyrimidones, i.e. 3-substituted-1,5-diazabicyclo(4.4.0)deca-2,5,7,9-tetraen-4-ones via reaction with 2-aminopyridine in environmentally friendly aqueous media is described. A facile, one-pot convenient transformation of the acetates of Baylis–Hillman adducts into fused pyrimidones, i.e. 3-substituted-1,5-diazabicyclo(4.4.0)deca-2,5,7,9-tetraen-4-ones via reaction with 2-aminopyridine in aqueous media is described.
ISSN:0040-4039
1873-3581
DOI:10.1016/S0040-4039(02)00802-X