Preparation and photophysical properties of halogenated silicon(IV) phthalocyanines substituted axially with poly(ethylene glycol) chains

A series of silicon(IV) phthalocyanines with two axial poly(ethylene glycol) chains SiPcX 8[(OCH 2CH 2) n OCH 3] 2 (X=H, Cl, Br; n≈16) have been prepared of which the photosensitizing properties are enhanced as the periphery of the macrocycle is substituted with heavier halogens. Incorporation of he...

Full description

Saved in:
Bibliographic Details
Published in:Tetrahedron letters 2003-02, Vol.44 (9), p.1967-1970
Main Authors: Lo, Pui-Chi, Wang, Shuangqing, Zeug, Andre, Meyer, Matthias, Röder, Beate, Ng, Dennis K.P
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A series of silicon(IV) phthalocyanines with two axial poly(ethylene glycol) chains SiPcX 8[(OCH 2CH 2) n OCH 3] 2 (X=H, Cl, Br; n≈16) have been prepared of which the photosensitizing properties are enhanced as the periphery of the macrocycle is substituted with heavier halogens. Incorporation of heavy halogen substituents onto the periphery of silicon(IV) phthalocyanines promotes intersystem crossing and enhances the singlet oxygen quantum yield of the macrocycles, making them desirable candidates for photodynamic therapy.
ISSN:0040-4039
1873-3581
DOI:10.1016/S0040-4039(03)00061-3