Akaterpin, a novel bioactive triterpene from the marine sponge Callyspongia sp

Akaterpin ( 1), an inhibitor of phosphatidylinositol-specific phospholipase C, was isolated from an acetone extract of the marine sponge, Callyspongia sp. Structural determination by 2D-NMR spectroscopy revealed that it was a novel triterpene with the hydroquinone disulfate. Akaterpin 1, a novel inh...

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Bibliographic Details
Published in:Tetrahedron letters 1997-02, Vol.38 (7), p.1201-1202
Main Authors: Fukami, Akiko, Ikeda, Yoko, Kondo, Shinichi, Naganawa, Hiroshi, Takeuchi, Tomio, Furuya, Shigeki, Hirabayashi, Yoshio, Shimoike, Kazuyuki, Hosaka, Saburo, Watanabe, Yoko, Umezawa, Kazuo
Format: Article
Language:English
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Summary:Akaterpin ( 1), an inhibitor of phosphatidylinositol-specific phospholipase C, was isolated from an acetone extract of the marine sponge, Callyspongia sp. Structural determination by 2D-NMR spectroscopy revealed that it was a novel triterpene with the hydroquinone disulfate. Akaterpin 1, a novel inhibitor of phosphatidylinositol-specific phospholipase C, was isolated from the acetone extract of a marine sponge.
ISSN:0040-4039
1873-3581
DOI:10.1016/S0040-4039(97)00016-6