Total syntheses of the diterpenoids (±)-verrucosan-2β-ol, (±)-neoverrucosan-5β-ol, and (±)-homoverrucosan-5β-ol. An approach to the synthesis of the sesterterpenoid variecolin

Efficient total syntheses of the racemic versions of the diterpenoids verrucosan-2β-ol ( 5), neoverrucosan-5β-ol ( 6), and homoverrucosan-5β-ol ( 7) are described. The production of the key intermediate 15 suggests a possible synthetic approach to the tetracyclic natural product variecolin ( 1). Gra...

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Bibliographic Details
Published in:Tetrahedron letters 1997-12, Vol.38 (51), p.8815-8818
Main Authors: Piers, Edward, Boulet, Serge L.
Format: Article
Language:English
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Summary:Efficient total syntheses of the racemic versions of the diterpenoids verrucosan-2β-ol ( 5), neoverrucosan-5β-ol ( 6), and homoverrucosan-5β-ol ( 7) are described. The production of the key intermediate 15 suggests a possible synthetic approach to the tetracyclic natural product variecolin ( 1). Graphic
ISSN:0040-4039
1873-3581
DOI:10.1016/S0040-4039(97)10507-X