An efficient and highly selective cleavage of N- tert-butoxycarbonyl group under microwave irradiation

A simple and high yielding method for the cleavage of t-Boc carbamates is described which occurs under mild and solvent-free conditions using microwave irradiation. A simple and high yielding method for the cleavage of t-Boc carbamates is described which occurs under mild and solvent-free conditions...

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Bibliographic Details
Published in:Tetrahedron letters 1998-07, Vol.39 (31), p.5631-5634
Main Authors: Bose, D.Subhas, Lakshminarayana, V.
Format: Article
Language:English
Subjects:
Chemoselectivity
Lewis acid catalyst
Microwave irradiation
tert-butylcarbamate
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Summary:A simple and high yielding method for the cleavage of t-Boc carbamates is described which occurs under mild and solvent-free conditions using microwave irradiation. A simple and high yielding method for the cleavage of t-Boc carbamates is described which occurs under mild and solvent-free conditions using microwave irradiation.
ISSN:0040-4039
1873-3581
DOI:10.1016/S0040-4039(98)01094-6