Amidine protection for solution phase library synthesis

The application of 4-methoxybenzyl-4-nitrophenylcarbonate as a reagent for the N-protection of amidinonaphthol has been demonstrated. The facile introduction of the 4-methoxybenzyloxycarbonyl group and the mildness of the deprotection conditions make this reagent well suited for the multiparallel so...

Full description

Saved in:
Bibliographic Details
Published in:Tetrahedron letters 1999-06, Vol.40 (26), p.4847-4850
Main Authors: Bailey, Christine, Baker, Emma, Hayler, Judy, Kane, Peter
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The application of 4-methoxybenzyl-4-nitrophenylcarbonate as a reagent for the N-protection of amidinonaphthol has been demonstrated. The facile introduction of the 4-methoxybenzyloxycarbonyl group and the mildness of the deprotection conditions make this reagent well suited for the multiparallel solution phase synthesis of substituted benzamidines. Graphic
ISSN:0040-4039
1873-3581
DOI:10.1016/S0040-4039(99)00891-6