Study of solubility of isoproturon by its complexation with β-cyclodextrin

The inclusion complexes of β-cyclodextrin–isoproturon were prepared using techniques such as kneading, co-evaporation, and co-precipitation. These complexes were characterised for physical properties and spectral studies such as UV, FTIR, and 1HNMR spectroscopy. To investigate the stoichiometry of t...

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Bibliographic Details
Published in:Chemosphere (Oxford) 2003-06, Vol.51 (8), p.811-816
Main Authors: Manolikar, M.K, Sawant, M.R
Format: Article
Language:English
Subjects:
beta-Cyclodextrins
Biological and medical sciences
Carcinogens - chemistry
Chemical control
Cyclodextrin
Cyclodextrins - chemistry
Dissolution rate study
Fundamental and applied biological sciences. Psychology
Herbicides - chemistry
Isoproturon
Magnetic Resonance Spectroscopy
Methylurea Compounds - chemistry
NMR spectroscopy
Parasitic plants. Weeds
Phase solubility study
Phenylurea Compounds
Phytopathology. Animal pests. Plant and forest protection
Solubility
Spectroscopy, Fourier Transform Infrared
Weeds
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Summary:The inclusion complexes of β-cyclodextrin–isoproturon were prepared using techniques such as kneading, co-evaporation, and co-precipitation. These complexes were characterised for physical properties and spectral studies such as UV, FTIR, and 1HNMR spectroscopy. To investigate the stoichiometry of the complexes Phase solubility method was adopted. Most of the complexes showed an increase in the dissolution rate of the herbicide. The best results were obtained when inclusion complexes were prepared by co-precipitation and co-evaporation method. Findings of this paper will allow the rational use of isoproturon with increase in its efficacy.
ISSN:0045-6535
1879-1298
DOI:10.1016/S0045-6535(03)00099-7