Preparation and antibacterial effects of Ag-SiO2 thin films by sol-gel method

• Published in: Biomaterials 2003-12, Vol.24 (27), p.4921-4928
• Main Authors: Jeon, Hyung-Jun, Yi, Sung-Chul, Oh, Seong-Geun
• Format: Article
• Language: English
• Subjects: Anti-Bacterial Agents - pharmacology; Coated Materials, Biocompatible - chemical synthesis; Coated Materials, Biocompatible - pharmacokinetics; Colony Count, Microbial; Equipment Contamination - prevention & control; Escherichia coli - cytology; Escherichia coli - drug effects; Materials Testing; Phase Transition; Silicon Dioxide - chemistry; Silver - chemistry; Silver - pharmacology; Staphylococcus aureus - cytology; Staphylococcus aureus - drug effects; Sterilization - methods; Surface Properties
• ISSN: 0142-9612
• DOI: 10.1016/s0142-9612(03)00415-0

In the present study, silver-doped silica thin films were successfully prepared by sol-gel method to apply for antibacterial materials. The starting solution was prepared from 1:0.24:3.75:2.2 molar ratios of Si(OC2H5)4):AgNO3:H2O:C2H5OCH2CH2OH and then the pH value controlled at 3 with 0.5 N HNO3 solution. The formation of silver-doped glassy silica thin films at various temperatures was investigated through infrared spectroscopy, ultraviolet-visible, scanning electron microscopy and X-ray diffraction. From these analysis data, it was found that silver ions were completely trapped in the silica matrix and their reduction could be achieved at 600 degrees C annealing temperature. The antibacterial effects of silica thin films against Escherichia coli and Staphylococcus aureus were examined by film attachment method. The coating films had an excellent antibacterial performance.