Improved solubility of β-cyclodextrin inclusion complexes by using liquid ammonia as a solvent and the possibility of asymmetric reduction

Dramatic improvement in the poor solubility of β-cyclodextrin (β-CD) and its inclusion complexes in water was achieved by using liquid ammonia (liq. NH 3) instead of water as the solvent. Asymmetric NaBH 4 reduction of the carbonyl groups of the inclusion complexes in liq. NH 3 was examined in a hom...

Full description

Saved in:
Bibliographic Details
Published in:Carbohydrate polymers 2002-03, Vol.47 (4), p.373-376
Main Authors: Matsuoka, Koji, Takahashi, Hiroyuki, Saito, Yosuke, Terunuma, Daiyo, Kuzuhara, Hiroyoshi
Format: Article
Language:English
Subjects:
Applied sciences
Asymmetric reduction
Cyclodextrins
Exact sciences and technology
Inclusion complexes
Liquid ammonia
Natural polymers
Physicochemistry of polymers
Starch and polysaccharides
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Dramatic improvement in the poor solubility of β-cyclodextrin (β-CD) and its inclusion complexes in water was achieved by using liquid ammonia (liq. NH 3) instead of water as the solvent. Asymmetric NaBH 4 reduction of the carbonyl groups of the inclusion complexes in liq. NH 3 was examined in a homogeneous condition to give the corresponding alcohols with moderate chirality.
ISSN:0144-8617
1879-1344
DOI:10.1016/S0144-8617(01)00189-8