Synthesis of new pyrrolo[1,2- a]quinoxalines: potential non-peptide glucagon receptor antagonists

Synthesis of new pyrrolo[1,2- a]quinoxaline derivatives was achieved starting from various nitroanilines or orthophenylenediamines. Their affinity towards glucagon receptors was evaluated

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Bibliographic Details
Published in:European journal of medicinal chemistry 1998-04, Vol.33 (4), p.293-308
Main Authors: Guillon, Jean, Dallemagne, Patrick, Pfeiffer, Bruno, Renard, Pierre, Manechez, Dominique, Kervran, Alain, Rault, Sylvain
Format: Article
Language:English
Subjects:
Biological and medical sciences
diabetes
General and cellular metabolism. Vitamins
glucagon receptor
Medical sciences
non-peptide antagonist
Pharmacology. Drug treatments
pyrrolo[1,2- a]quinoxaline derivative
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Description
Summary:Synthesis of new pyrrolo[1,2- a]quinoxaline derivatives was achieved starting from various nitroanilines or orthophenylenediamines. Their affinity towards glucagon receptors was evaluated
ISSN:0223-5234
1768-3254
DOI:10.1016/S0223-5234(98)80063-9