Markers of haemostatic system activation in 80 patients with deep venous thrombosis submitted to fibrinolytic therapy

Plasma levels of thrombin-antithrombin III complexes (TAT) and prothrombin activation fragment F1+2(F1+2) were analysed in 80 patients with phlebographic proven acute deep vein thrombosis (DVT). TAT and F1+2 levels were measured at the time of diagnosis, at 6 and 24 h after the beginning of urokinas...

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Bibliographic Details
Published in:Fibrinolysis 1995, Vol.9 (4), p.231-236
Main Authors: López-Fernández, M.F., Batlle, J., Soler, R., Díaz, M. Marini
Format: Article
Language:English
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Summary:Plasma levels of thrombin-antithrombin III complexes (TAT) and prothrombin activation fragment F1+2(F1+2) were analysed in 80 patients with phlebographic proven acute deep vein thrombosis (DVT). TAT and F1+2 levels were measured at the time of diagnosis, at 6 and 24 h after the beginning of urokinase infusion, and at the end of fibrinolytic therapy. Patients were allocated into two subgroups according to their thrombus size: one group of 45 patients with a Marder score >25, and a second group of 35 patients with a score
ISSN:0268-9499
DOI:10.1016/S0268-9499(08)80064-1