Treatment of alcohol withdrawal with gabapentin

Gabapentin is an anticonvulsant agent, also effective in the treatment of mood disorders and anxiety disorders. Three cases of alcohol withdrawal treated with gabapentin are presented. All patients received gabapentin 400 mg tid for 3 days, 400 mg bid for 1 day, and finally 400 mg for 1 day. Withdra...

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Bibliographic Details
Published in:Progress in neuro-psychopharmacology & biological psychiatry 2002, Vol.26 (1), p.197-199
Main Authors: Bozikas, Vasilis, Petrikis, Petros, Gamvrula, Katerina, Savvidou, Ioanna, Karavatos, Athanasios
Format: Article
Language:English
Subjects:
Acetates - therapeutic use
Adult
Alcohol withdrawal
Alcoholism and acute alcohol poisoning
Amines
Anti-Anxiety Agents - therapeutic use
Anticonvulsant
Biological and medical sciences
Cyclohexanecarboxylic Acids
Ethanol - adverse effects
Gabapentin
gamma-Aminobutyric Acid
Humans
Male
Medical sciences
Middle Aged
Mood Disorders - drug therapy
Mood Disorders - etiology
Substance Withdrawal Syndrome - drug therapy
Toxicology
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Summary:Gabapentin is an anticonvulsant agent, also effective in the treatment of mood disorders and anxiety disorders. Three cases of alcohol withdrawal treated with gabapentin are presented. All patients received gabapentin 400 mg tid for 3 days, 400 mg bid for 1 day, and finally 400 mg for 1 day. Withdrawal symptoms subsided and no adverse effects were observed. The possible effectiveness of gabapentin in the treatment of alcohol withdrawal warrants further investigation by systematic and well-designed studies.
ISSN:0278-5846
1878-4216
DOI:10.1016/S0278-5846(01)00234-2