Malignant mixed mesodermal tumor arising in a benign cystic teratoma

The occurrence of sarcoma in a benign cystic teratoma is very rare. We report the first poorly differentiated, malignant mixed mesodermal tumor with a component of rhabdomyosarcoma to arise in a benign cystic teratoma of the ovary. The tumor was staged as FIGO IC due to capsule invasion. Although co...

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Bibliographic Details
Published in:European journal of obstetrics & gynecology and reproductive biology 1999-04, Vol.83 (2), p.191-194
Main Authors: Ergeneli, Mehmet H., Demirhan, Beyhan, Hakan Duran, E., Coskun, Mehmet
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Bone Neoplasms - diagnosis
Bone Neoplasms - secondary
Dermoid
Fatal Outcome
Female
Female genital diseases
Gynecology. Andrology. Obstetrics
Humans
Malignant mixed mesodermal tumor
Malignant transformation
Medical sciences
Mixed Tumor, Mesodermal - diagnosis
Mixed Tumor, Mesodermal - secondary
Mixed Tumor, Mesodermal - therapy
Ovarian Neoplasms - diagnosis
Ovarian Neoplasms - pathology
Ovarian Neoplasms - therapy
Ovary
Rhabdomyosarcoma
Scapula
Teratoma - diagnosis
Teratoma - secondary
Teratoma - therapy
Tropical medicine
Tumors
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Summary:The occurrence of sarcoma in a benign cystic teratoma is very rare. We report the first poorly differentiated, malignant mixed mesodermal tumor with a component of rhabdomyosarcoma to arise in a benign cystic teratoma of the ovary. The tumor was staged as FIGO IC due to capsule invasion. Although combination chemotherapy of cisplatin, ifosfamide and mesna, was instituted, the disease took a rapidly progressive course. After an unusual metastasis to the scapula was detected, the patient deteriorated and died in the forth postoperative month.
ISSN:0301-2115
1872-7654
DOI:10.1016/S0301-2115(98)00338-8