Ovarian Ependymoma. A Case Report

We present the case of a 30-year-old woman who was referred to our institution with an erroneous diagnosis of poorly differentiated carcinoma of the ovary. The patient presented pelvic pain for one year prior to surgery. A second laparotomy revealed a bilateral pure ovarian ependymoma that infiltrat...

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Bibliographic Details
Published in:Pathology, research and practice research and practice, 2000, Vol.196 (8), p.595-599
Main Authors: Garcia-Barriola, Victoria, de Gomez, Mirian Naranjo, Suarez, Jose A., Lara, Carmen, Gonzalez, Jesus E., Garcia-Tamayo, Jorge
Format: Article
Language:English
Subjects:
Adult
Combined Modality Therapy
Diagnosis, Differential
Diagnostic Errors
Ependymoma
Ependymoma - metabolism
Ependymoma - pathology
Ependymoma - surgery
Female
Glial Fibrillary Acidic Protein - metabolism
Humans
Monodermal teratoma
Neoplasm Invasiveness
Ovarian
Ovarian Neoplasms - metabolism
Ovarian Neoplasms - pathology
Ovarian Neoplasms - surgery
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Summary:We present the case of a 30-year-old woman who was referred to our institution with an erroneous diagnosis of poorly differentiated carcinoma of the ovary. The patient presented pelvic pain for one year prior to surgery. A second laparotomy revealed a bilateral pure ovarian ependymoma that infiltrated the uterus and presented implants on the omentum. Differential diagnosis included mainly endometrioid and small cell carcinoma of the ovary. Presence of typical ependymal rosettes and positivity to GFAP confirmed the diagnosis of ependy-moma. Other teratomatous elements were not observed. Ovarian ependymomas are rare tumors; only eight cases, to our knowledge, have been reported in the literature. They have a favorable prognosis; patients with advanced stage disease are reported alive and well after treatment with surgery and chemotherapy
ISSN:0344-0338
1618-0631
DOI:10.1016/S0344-0338(00)80035-7