Biological activities of crude plant extracts from Vitex trifolia L . (Verbenaceae)

Biological assays of Vitex trifolia L. organic extracts have shown relevant activities. Hexanic and dichloromethanic (DCM) extracts, when prepared from stems and foliage, have proved to be very toxic against several cancer cell lines in culture (SQC-1 UISO, OVCAR-5, HCT-15 COLADCAR, and KB). Also, a...

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Bibliographic Details
Published in:Journal of ethnopharmacology 1999-10, Vol.67 (1), p.37-44
Main Authors: Hernández, M.M., Heraso, C., Villarreal, M.L., Vargas-Arispuro, I., Aranda, E.
Format: Article
Language:English
Subjects:
Animals
Anti-Bacterial Agents
Anti-Infective Agents - pharmacology
Antifeeding
Antifungal Agents - pharmacology
Antimicrobial activity
Antineoplastic Agents, Phytogenic - pharmacology
Bacteria - drug effects
Bacteria - growth & development
Biological and medical sciences
Cytotoxic activity
Drug Screening Assays, Antitumor
Feeding Behavior - drug effects
Fungi - drug effects
Fungi - growth & development
General pharmacology
Humans
Insecticides - pharmacology
Medical sciences
Medicine, Traditional
Mexico
Microbial Sensitivity Tests
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Phytotherapy
Plant Extracts - pharmacology
Plant Leaves - chemistry
Plant Stems - chemistry
Plants, Medicinal
Spodoptera - drug effects
Spodoptera - physiology
Tumor Cells, Cultured - drug effects
Verbenaceae
Vitex
Vitex trifolia
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Summary:Biological assays of Vitex trifolia L. organic extracts have shown relevant activities. Hexanic and dichloromethanic (DCM) extracts, when prepared from stems and foliage, have proved to be very toxic against several cancer cell lines in culture (SQC-1 UISO, OVCAR-5, HCT-15 COLADCAR, and KB). Also, an important antifeeding activity against the insect pest Spodoptera frugiperda (Lepidoptera: Noctuidae) was recorded. The hexanic extract from leaves completely inhibited the growth of the fungal plant pathogen Fusarium sp . within the first 2 days of the experiment, but dropped significantly at day 6 (15% inhibition). The potential of V. trifolia for several uses is discussed.
ISSN:0378-8741
1872-7573
DOI:10.1016/S0378-8741(99)00041-0