Biphasic course of infant botulism

The syndrome of infant botulism, characterized by constipation, poor feeding, hypotonia, poor head control, and bulbar involvement, is typically a monophasic disease. We describe a 7-month-old infant with a recurrence of illness 13 days after resolution of the presenting signs. The source of infecti...

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Bibliographic Details
Published in:Pediatric neurology 2000-10, Vol.23 (4), p.338-339
Main Authors: Ravid, Sarit, Maytal, Joseph, Eviatar, Lydia
Format: Article
Language:English
Subjects:
Bacterial diseases
Bacterial diseases of the nervous system. Bacterial myositis
Biological and medical sciences
Botulism - complications
Botulism - physiopathology
Botulism - prevention & control
Clostridium botulinum
Constipation - etiology
Female
Human bacterial diseases
Humans
Infant
Infectious diseases
Medical sciences
Secondary Prevention
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Summary:The syndrome of infant botulism, characterized by constipation, poor feeding, hypotonia, poor head control, and bulbar involvement, is typically a monophasic disease. We describe a 7-month-old infant with a recurrence of illness 13 days after resolution of the presenting signs. The source of infection was unknown and the only potential risk factors were exclusive breastfeeding and decreased bowel movements, which by themselves cannot explain the recurrence. Although treatment with botulism immunoglobulin is now suggested for the acute phase of infantile botulism, its use for recurrence is controversial.
ISSN:0887-8994
1873-5150
DOI:10.1016/S0887-8994(00)00204-6