Effect of Highly Active Antiretroviral Therapy on Oral Manifestations of Human Immunodeficiency Virus Infection in Japanese Patients

Objective: Protease inhibitors became available in Japan in April 1997. This study was performed to compare changes in oral manifestations between the pre- and post-highly active antiretroviral therapy periods in Japanese patients with human immunodeficiency virus infection. Patients and Methods: Tw...

Full description

Saved in:
Bibliographic Details
Published in:The Asian journal of oral and maxillofacial surgery 2002-03, Vol.14 (1), p.21-26
Main Authors: Morimoto, Yoshinari, Ikeuchi, Masako, Yamamoto, Kazuhiko, Kirita, Tadaaki, Sugimura, Masahito
Format: Article
Language:English
Subjects:
Antiretroviral therapy
highly active
Human immunodeficiency virus infection
Oral manifestations
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective: Protease inhibitors became available in Japan in April 1997. This study was performed to compare changes in oral manifestations between the pre- and post-highly active antiretroviral therapy periods in Japanese patients with human immunodeficiency virus infection. Patients and Methods: Twenty seven Japanese patients with human immunodeficiency virus infection were investigated. The backgrounds (age, sex, and risk group), immune status at first visit and changes with time, associated systemic diseases, and oral manifestations were examined using patients' clinical records. Results: Although pseudomembranous candidiasis decreased significantly (p < 0.05), other oral manifestations did not change. These results were obtained for patients with CD4+ lymphocytes of 499 to 200/mm3, with no change recorded for patients with CD4+ lymphocytes of
ISSN:0915-6992
2212-1897
DOI:10.1016/S0915-6992(02)80017-6