A model of sleep spindles generation

A model of thalamic system combining properties of lumped and single representative neuron type models was constructed. It includes data on intrinsic ionic currents and allows for direct comparison of model output with observables derived from the scalp EEG. The model accounts for: waxing and waning...

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Bibliographic Details
Published in:Neurocomputing (Amsterdam) 2001-06, Vol.38, p.1619-1625
Main Authors: Żygierewicz, J, Suffczyński, P, Blinowska, K
Format: Article
Language:English
Subjects:
EEG modeling
Sleep spindles
Thalamic system
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Summary:A model of thalamic system combining properties of lumped and single representative neuron type models was constructed. It includes data on intrinsic ionic currents and allows for direct comparison of model output with observables derived from the scalp EEG. The model accounts for: waxing and waning of sleep spindles, topographical differences in their spectra and in the slow rhythm of their reappearance in the scalp EEG, differences in the rhythm of spindles’ reappearance reported in vivo and in vitro. The model also describes rhythms in awake and in deep sleep EEG.
ISSN:0925-2312
1872-8286
DOI:10.1016/S0925-2312(01)00516-1