Efficient synthesis of antisense oligodeoxyribonucleotide phosphorothioates

Efficient and economical synthesis of antisense oligodeoxyribonucleotide phosphorothioates utilizing 2 equivalents of phosphoramidite synthon is reported. Efficient and economical synthesis of antisense oligodeoxyribonucleoside phosphorothioates utilizing two equivalents of phosphoramidite synthon i...

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Bibliographic Details
Published in:Bioorganic & medicinal chemistry letters 1994-08, Vol.4 (16), p.2017-2022
Main Authors: Andrade, Mark, Scozzari, Anthony, Cole, Douglas L., Ravikumar, Vasulinga T.
Format: Article
Language:English
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Summary:Efficient and economical synthesis of antisense oligodeoxyribonucleotide phosphorothioates utilizing 2 equivalents of phosphoramidite synthon is reported. Efficient and economical synthesis of antisense oligodeoxyribonucleoside phosphorothioates utilizing two equivalents of phosphoramidite synthon is reported.
ISSN:0960-894X
1464-3405
DOI:10.1016/S0960-894X(01)80555-2