Synthesis of thiophenes and thieno[3,2-c]pyran-4-ones as antileishmanial and antifungal agents

A series of highly functionalized thiophene ( 2) and thieno[3,2-c]pyran-4-one( 4) derivatives have been synthesized and evaluated for their antileishmanial and antifungal activities. Antileishmanial and antifungal activities of newly synthesized thiophenes( 2) and thieno[3, 2-c]pyran-4-ones( 4) are...

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Bibliographic Details
Published in:Bioorganic & medicinal chemistry letters 1997-12, Vol.7 (24), p.3101-3106
Main Authors: Ram, Vishnu J., Goel, Atul, Shukla, P.K., Kapil, A.
Format: Article
Language:English
Subjects:
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antiparasitic agents
Biological and medical sciences
Medical sciences
Pharmacology. Drug treatments
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Summary:A series of highly functionalized thiophene ( 2) and thieno[3,2-c]pyran-4-one( 4) derivatives have been synthesized and evaluated for their antileishmanial and antifungal activities. Antileishmanial and antifungal activities of newly synthesized thiophenes( 2) and thieno[3, 2-c]pyran-4-ones( 4) are described.
ISSN:0960-894X
1464-3405
DOI:10.1016/S0960-894X(97)10153-6