Interaction of cyanine dyes with nucleic acids. XII.β-substituted carbocyanines as possible fluorescent probes for nucleic acids detection

Results of investigations of fluorescent properties of a β-substituted carbocyanine and its complexes with nucleic acids in comparison with those for the unsubstituted dye are presented. Carbocyanine substituted in polymethine chain has shown promising properties for use as a fluorescent probe in ho...

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Bibliographic Details
Published in:Bioorganic & medicinal chemistry letters 1999-06, Vol.9 (12), p.1677-1678
Main Authors: Yarmoluk, Sergiy M, Kovalska, Vladyslava B, Lukashov, Sergiy S, Slominskii, Yury L
Format: Article
Language:English
Subjects:
Analytical, structural and metabolic biochemistry
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
General aspects, investigation methods
Nucleic acids
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Summary:Results of investigations of fluorescent properties of a β-substituted carbocyanine and its complexes with nucleic acids in comparison with those for the unsubstituted dye are presented. Carbocyanine substituted in polymethine chain has shown promising properties for use as a fluorescent probe in homogeneous systems of nucleic acids detection.
ISSN:0960-894X
1464-3405
DOI:10.1016/S0960-894X(99)00253-X