Anatomy of SUV

Standardized uptake value (SUV) for [F-18]fluorodeoxyglucose (FDG) studies that is commonly used to differentiate malignant from benign tumors and to assess the efficacy of therapy is reviewed as a simplified calculation of the more general modeling approach. Based on such a basis, the merits and li...

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Bibliographic Details
Published in:Nuclear medicine and biology 2000-10, Vol.27 (7), p.643-646
Main Author: HUANG, Sung-Cheng
Format: Article
Language:English
Subjects:
Biological and medical sciences
Contrast media. Radiopharmaceuticals
Glucose utilization rate
Investigative techniques, diagnostic techniques (general aspects)
Kinetic modeling
Medical sciences
Miscellaneous. Technology
Pharmacology. Drug treatments
Radionuclide investigations
Tracer
Tumor
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Summary:Standardized uptake value (SUV) for [F-18]fluorodeoxyglucose (FDG) studies that is commonly used to differentiate malignant from benign tumors and to assess the efficacy of therapy is reviewed as a simplified calculation of the more general modeling approach. Based on such a basis, the merits and limitations of the SUV approach is examined with reference to literature reports on tumor uptake of FDG. Results indicate the complexity and large variation of glucose uptake mechanism in tumors. Consistently performed procedures and more basic studies are needed to improve the utility of FDG SUV.
ISSN:0969-8051
1872-9614
DOI:10.1016/S0969-8051(00)00155-4