Multicenter randomly controlled trial on acupoint injection therapy with Chinese herbal medicines for oculomotor paralysis

• Published in: World journal of acupuncture-moxibustion 2013, Vol.23 (1), p.9-14
• Main Authors: GUO, Shu-qin, REN, Hong, CAO, Yan-xia, WANG, Lin
• Format: Article
• Language: English
• Subjects: acupoint injection; injection with Chinese traditional medicines; multicenter randomized controlled trial; paralysis of oculomotor nerve
• ISSN: 1003-5257
• DOI: 10.1016/S1003-5257(13)60003-3

To evaluate the clinical effect of acupoint injection therapy for paralysis of oculomotor nerve with Chinese herbal medicines. A total number of 456 patients from 3 centers with paralysis of oculomotor nerve were randomly divided into an acupoint injection group and a control group with 228 cases each. Patients in the acupoint injection group were treated with injection of Chinese herbal medicines to Jīngmíng (▪ BL 1), Yángbái (▪ GB 14), Sìbái (▪ ST 2), Tóngziliáo (▪ GB 1) on the affected side, and Gĕnshū (▪ BL 18) on both sides, Compound Angelica Injection was the main drug, and the corresponding acupoints and other injection drugs were also used according to differentiation of syndrome. Patients in the control group were treated with common western medicine. The treatment was given once a day, 10 times constituted one course with 3 days of interval. After 3 courses, the effect was assessed. TCM syndrome score, eyeball movement degree, the sizes of oculi rimae and pupil of the two groups were recorded before and after treatment. The effective rate of acupoint injection group was 91.7% (209/228), and that of the control group was 73.6% (168/228). There was statistical significance in comparing the difference between the two groups (P