Bone integration properties of antibacterial biomimetic porous titanium implants

A novel antibacterial biomimetic porous titanium implant with good osseointegration was prepared by freeze-casting and thermal oxidation. Bone integration properties of the porous titanium implant were evaluated by cell proliferation assay, alkaline phosphatase activity assay, X-ray examination and...

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Bibliographic Details
Published in:Transactions of Nonferrous Metals Society of China 2017-09, Vol.27 (9), p.2007-2014
Main Authors: WANG, Guo-hui, FU, Hua, ZHAO, Yan-zhong, ZHOU, Ke-chao, ZHU, Shai-hong
Format: Article
Language:English
Subjects:
antibacterial function
freeze-casting
osseointegration
porous titanium implant
surface modification
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Summary:A novel antibacterial biomimetic porous titanium implant with good osseointegration was prepared by freeze-casting and thermal oxidation. Bone integration properties of the porous titanium implant were evaluated by cell proliferation assay, alkaline phosphatase activity assay, X-ray examination and hard bone tissue biopsy. The in vitro cell proliferation and the level of differentiation of the group with a modified nano-porous implant surface were significantly higher than those in the group without surface modification and the dense titanium control group (P
ISSN:1003-6326
DOI:10.1016/S1003-6326(17)60225-5