Yellow nail syndrome associated with thiol compound therapy for rheumatoid arthritis. Two case reports

Yellow nail syndrome is characterized by ungual dystrophy, lower limb lymphedema, and pleural effusions or bronchiectasis. Rheumatoid arthritis is the autoimmune disorder most often associated with yellow nail syndrome. We report two new cases of yellow nail syndrome in patients receiving thiol comp...

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Bibliographic Details
Published in:Joint, bone, spine : revue du rhumatisme bone, spine : revue du rhumatisme, 2002-06, Vol.69 (4), p.406-408
Main Authors: Lehuédé, Gaëlle, Toussirot, Eric, Despaux, Jacques, Michel, Fabrice, Wendling, Daniel
Format: Article
Language:English
Subjects:
Aged
Antirheumatic Agents - adverse effects
Arthritis, Rheumatoid - drug therapy
D-penicillamine therapy
Female
Humans
Nail Diseases - chemically induced
Penicillamine - adverse effects
rheumatoid arthritis
thiol derivatives
Tiopronin - adverse effects
yellow nail syndrome
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Summary:Yellow nail syndrome is characterized by ungual dystrophy, lower limb lymphedema, and pleural effusions or bronchiectasis. Rheumatoid arthritis is the autoimmune disorder most often associated with yellow nail syndrome. We report two new cases of yellow nail syndrome in patients receiving thiol compound therapy for rheumatoid arthritis. Eight similar cases have been reported since 1979, suggesting a possible causative effect of this class of drugs.
ISSN:1297-319X
DOI:10.1016/S1297-319X(02)00421-9