Protein–polysaccharide interactions: phase-ordering kinetics, thermodynamic and structural aspects

If the most important parameters affecting protein–polysaccharide interactions are now well documented, recent advances concern the structure-building kinetics, thermodynamics and structure of mixtures. As far as complex coacervation is concerned, experimental tools such as light scattering techniqu...

Full description

Saved in:
Bibliographic Details
Published in:Current opinion in colloid & interface science 2003-11, Vol.8 (4), p.401-414
Main Authors: Turgeon, S.L, Beaulieu, M, Schmitt, C, Sanchez, C
Format: Article
Language:English
Subjects:
Complex coacervation
Kinetics
Phase separation
Protein–polysaccharide interactions
Structure
Thermodynamic incompatibility
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:If the most important parameters affecting protein–polysaccharide interactions are now well documented, recent advances concern the structure-building kinetics, thermodynamics and structure of mixtures. As far as complex coacervation is concerned, experimental tools such as light scattering techniques, confocal and electron microscopy and high-sensitivity or isothermal titration calorimetry have brought insights on the molecular structure of the systems and gave access to thermodynamic parameters. These experimental data, combined with intensive numerical simulations on polyelectrolyte systems, are used to build up various models of protein–polysaccharide interaction taking into account both intrinsic and extrinsic parameters. In the case of thermodynamic incompatibility, probing interfaces of phase-separated systems is bringing some insights on the spatial and temporal behavior of such systems. The recent use of w/w emulsion like approach successfully allowed better control of the morphology of segregative phase-separated systems.
ISSN:1359-0294
1879-0399
DOI:10.1016/S1359-0294(03)00093-1