The biological chemistry of lead

Recent biophysical studies on the interactions between lead and recombinant proteins and peptides that naturally bind zinc or calcium have provided unparalleled insights into the biological chemistry and molecular toxicology of lead. These studies lay the foundation for the rational design of improv...

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Bibliographic Details
Published in:Current Opinion in Chemical Biology 2001-04, Vol.5 (2), p.223-227
Main Author: Godwin, Hilary Arnold
Format: Article
Language:English
Subjects:
Animals
bioavailability
bioinorganic
Biological Availability
Calcium - chemistry
Calcium - metabolism
calcium proteins
heavy metal
Humans
Lead
Lead - chemistry
Lead - metabolism
Lead Poisoning - diagnosis
Lead Poisoning - therapy
Porphobilinogen Synthase - chemistry
Porphobilinogen Synthase - metabolism
Protein Binding - physiology
Protein Kinase C - chemistry
Protein Kinase C - metabolism
Zinc - chemistry
Zinc - metabolism
zinc proteins
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Description
Summary:Recent biophysical studies on the interactions between lead and recombinant proteins and peptides that naturally bind zinc or calcium have provided unparalleled insights into the biological chemistry and molecular toxicology of lead. These studies lay the foundation for the rational design of improved methods for detecting and treating lead poisoning.
ISSN:1367-5931
1879-0402
DOI:10.1016/S1367-5931(00)00194-0