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An efficient method for activation and recycling of trityl resins

A mild and efficient method for activation and recycling of trityl chloride resins has been developed. The recycling is performed under mild reaction conditions utilizing thionyl chloride as chlorinating agent. The method is useful for the recycling of the resin during solid phase peptide and organi...

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Bibliographic Details
Published in:Reactive & functional polymers 1999-07, Vol.41 (1), p.111-114
Main Authors: Harre, Michael, Nickisch, Klaus, Tilstam, Ulf
Format: Article
Language:English
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Summary:A mild and efficient method for activation and recycling of trityl chloride resins has been developed. The recycling is performed under mild reaction conditions utilizing thionyl chloride as chlorinating agent. The method is useful for the recycling of the resin during solid phase peptide and organic synthesis.
ISSN:1381-5148
DOI:10.1016/S1381-5148(99)00039-5