Acute cardiac failure in neuroleptic malignant syndrome

We present a case of rapid onset acute cardiac failure developing as part of Neuroleptic malignant syndrome in a 35‐year‐old woman following treatment with Thioridazine and Lithium. Post mortem histology of cardiac and skeletal muscle showed similar changes of focal cellular necrosis and vacuolation...

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Bibliographic Details
Published in:European journal of heart failure 2003-08, Vol.5 (4), p.575-578
Main Authors: Sparrow, Patrick, Murnaghan, Dermot, Kearney, Peter, Hogan, John, Sheppard, Mary N.
Format: Article
Language:English
Subjects:
acute cardiac failure
Adult
Fatal Outcome
Female
Heart Failure - etiology
Heart Failure - pathology
Humans
Muscle Cells - pathology
Muscle, Skeletal - pathology
Myocardium - pathology
myocyte necrosis
Necrosis
neuroleptic malignant syndrome
Neuroleptic Malignant Syndrome - complications
Neuroleptic Malignant Syndrome - pathology
vacuolation
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Summary:We present a case of rapid onset acute cardiac failure developing as part of Neuroleptic malignant syndrome in a 35‐year‐old woman following treatment with Thioridazine and Lithium. Post mortem histology of cardiac and skeletal muscle showed similar changes of focal cellular necrosis and vacuolation suggesting a common disease process.
ISSN:1388-9842
1879-0844
DOI:10.1016/S1388-9842(03)00036-9