Low-Dose Dobutamine Gated SPECT Analysis of Left Ventricular Segmental Wall Thickening in Ischemic Cardiomyopathy

The objective of this study was to use low-dose dobutamine (LDD) gated single-photon emission computed tomography (SPECT) to evaluate segmental thickening of the left ventricle (LV) and its relationship with changes in ejection fraction (EF) and ventricular volumes in patients with ischemic cardiomy...

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Bibliographic Details
Published in:Revista española de cardiologia 2008-10, Vol.61 (10), p.1061-1069
Main Authors: Candell-Riera, Jaume, Romero-Farina, Guillermo, Milá, Marta, Aguadé-Bruix, Santiago
Format: Article
Language:English
Subjects:
Bajas dosis de dobutamina
Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography
Dobutamine - administration & dosage
Engrosamiento segmentario
Female
Gated SPECT
Heart Ventricles - diagnostic imaging
Heart Ventricles - pathology
Humans
Ischemic cardiomyopathy
Low-dose dobutamine
Male
Middle Aged
Miocardiopatía isquémica
Myocardial Ischemia - diagnostic imaging
Myocardial Ischemia - pathology
Prospective Studies
Segmental thickening
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Summary:The objective of this study was to use low-dose dobutamine (LDD) gated single-photon emission computed tomography (SPECT) to evaluate segmental thickening of the left ventricle (LV) and its relationship with changes in ejection fraction (EF) and ventricular volumes in patients with ischemic cardiomyopathy. This prospective multicenter study involved 89 patients with ischemic cardiomyopathy (ie, EF ≤ 40%) who underwent LDD gated-SPECT at rest. The LV was divided into 17 segments and systolic thickening was assessed in a total of 1513 segments during LDD infusion. A significant increase in LVEF (33.2% vs30.8%; P
ISSN:1885-5857
1885-5857
1579-2242
DOI:10.1016/S1885-5857(09)60009-8