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Three-Dimensional Impedance Mapping as an Aid to Circumferential Pulmonary Vein Isolation in Paroxysmal Atrial Fibrillation

During circumferential pulmonary vein isolation, radiofrequency lesions are created in the transition zone between the left atrium and the pulmonary veins, outside the ostia, to avoid stenosis. Three-dimensional impedance maps were constructed for 25 patients with paroxysmal atrial fibrillation. In...

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Published in:Revista española de cardiología (English ed.) 2009-03, Vol.62 (3), p.315-319
Main Authors: Pedrote, Alonso, Arana-Rueda, Eduardo, García-Riesco, Lorena, Jiménez-Velasco, Adriano, Sánchez-Brotons, Juan, Arizón-Muñoz, José M., Fernández-Pérez, José M., Frutos-López, Manuel
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Language:English
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Summary:During circumferential pulmonary vein isolation, radiofrequency lesions are created in the transition zone between the left atrium and the pulmonary veins, outside the ostia, to avoid stenosis. Three-dimensional impedance maps were constructed for 25 patients with paroxysmal atrial fibrillation. In the first 15 patients, impedance was measured inside the pulmonary veins (165.4 [7.5] Ω), the ostium (141.6 [7.3] Ω), and the left atrium (131.09 [8.3] Ω). An impedance of 136 Ω identified the outer limit of the atrium (area under the receiver operating characteristic curve, 0.85). In the subsequent 10 patients, a single operator who was blinded to the anatomic position of the catheter tip was able to determine, by impedance measurement alone, whether the point targeted for radiofrequency ablation was in the left atrium or the ostium of the pulmonary vein. The positive predictive value for identifying the left atrium was 91% and the negative predictive value was 73%. In patients with paroxysmal atrial fibrillation, threedimensional impedance mapping was helpful in guiding circumferential pulmonary vein isolation. En el aislamiento circunferencial de las venas pulmonares, se realizan lesiones de radiofrecuencia en la zona de transición auricular y venosa, fuera de los ostia, para evitar las estenosis. Se construyó un mapa tridimensional de impedancias en 25 pacientes con fibrilación auricular paroxística. En los 15 primeros se midieron las impedancias del interior de las venas (165,4 ± 7,5 Ω), el ostium (141,6 ± 7,3 Ω) y la aurícula izquierda (131,09 ± 8,3 Ω). Una impedancia de 136 Ω definía el límite auricular (área bajo la curva ROC = 0,85). En los siguientes 10 pacientes, un operador que desconocía la posición anatómica del catéter clasificó por la impedancia los puntos para aplicar radiofrecuencia como aurícula izquierda u ostium de vena pulmonar, con valor predictivo positivo del 91% y negativo del 73% para identificar aurícula izquierda. En pacientes con fibrilación auricular paroxística, los mapas tridimensionales de impedancia son de ayuda para guiar el aislamiento circunferencial de las venas pulmonares.
ISSN:1885-5857
1885-5857
DOI:10.1016/S1885-5857(09)71563-4