Mechanism of the decreased food consumption and weight gain in rats following consumption of aqueous extract of the calyx of Hibiscus sabdariffa during pregnancy

• Published in: Asian Pacific journal of tropical medicine 2010-03, Vol.3 (3), p.185-188
• Main Authors: Iyare, Eghosa E, Adegoke, Olufeyi A, Nwagha, Uchenna I
• Format: Article
• Language: English
• Subjects: consumption; Fluid; Fluid consumption; Food; Food consumption; gain; Hibiscus; Hibiscus sabdariffa; Mechanism; Plasma; Plasma sodium; Pregnancy; sabdariffa; sodium; Weight; Weight gain
• ISSN: 1995-7645; 2352-4146
• DOI: 10.1016/S1995-7645(10)60005-3

<正>Objective:To investigate the possible mechanisms of the decreasing fluid and food consumption following Hibiscus sabdariffa(HS) consumption.Methods:On the 1st day of pregnancy,rats were randomly divided into three groups with six animals per each group.One group was given tap water,one was given with extract at 0.6 g/100 mL while the third group was given with extract at 1.8 g/100 mL as their drinking solution.All groups received normal rat chow and drinking solution ad libitum.Fluid& food intake and weight were measured daily throughout pregnancy and Na~+ concentration in plasma was determined on the 18th day of pregnancy.Results:Results showed decreased fluid and food consumption,decreased weight gain and increased sodium ion concentration in plasma of rats with HS extract compared with the control group.Conclusions: Consumption of aqueous extract of the calyx of HS during pregnancy decreases food consumption and weight gain through mechanisms that may depend on Na~+ in HS content and elevating Na~+ concentration.