Sinonasal adenocarcinomas: our experience

Sinonasal adenocarcinoma is a rare epithelial cancer of the nasal cavities and paranasal sinuses and exposure to sawdust particles is a strong aetiological factor. Seventy-nine patients (78 men and 1 woman) operated on between 1986 and 2002 were studied. In 62 patients (78.5 %) there was a history o...

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Bibliographic Details
Published in:Acta otorrinolaringológica española 2008-05, Vol.59 (5), p.235-238
Main Authors: Llorente, José Luis, Núñez, Faustino, Rodrigo, Juan Pablo, Fernández León, Ramón, Alvarez, César, Hermsen, Mario, Suárez, Carlos
Format: Article
Language:Spanish
Subjects:
Adenocarcinoma - pathology
Adult
Aged
Aged, 80 and over
Dust
Female
Humans
Male
Middle Aged
Paranasal Sinus Neoplasms - pathology
Risk Factors
Wood
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Summary:Sinonasal adenocarcinoma is a rare epithelial cancer of the nasal cavities and paranasal sinuses and exposure to sawdust particles is a strong aetiological factor. Seventy-nine patients (78 men and 1 woman) operated on between 1986 and 2002 were studied. In 62 patients (78.5 %) there was a history of exposure to wood dust. The clinical factors presenting statistical significance in the multivariate analysis with prognosis were: the exclusive invasion of the middle concha (as good prognosis), recurrence and invasion of the dura mater (as bad prognosis). The actuarial survival rate was 36 % at 5 years falling to 28 % at 10 years. Exposure to wood dust, even over a short period of time, must be considered as a high risk factor for the development of a sinonasal adenocarcinoma. This tumour must be ruled out in all patients suffering any type of sinonasal pathology.
ISSN:0001-6519
2173-5735
2173-5735
DOI:10.1016/S2173-5735(08)70229-1