In vitro antimicrobial activity of Caesalpinia sappan L

• Published in: Asian Pacific journal of tropical biomedicine 2012-01, Vol.2 (1), p.S136-S139
• Main Authors: Srinivasan, Rajendran, selvam, Govindarasu Ganapathy, Karthik, Sakthivel, Mathivanan, Krishnamurthy, Baskaran, Ramaiya, Karthikeyan, Mariappan, Gopi, Muchukathan, Govindasamy, Chinnavenkataraman
• Format: Article
• Language: English
• Subjects: Antimicrobial activity; Caesalpinia sappan; Phytochemical analysis
• ISSN: 2221-1691; 2588-9222
• DOI: 10.1016/S2221-1691(12)60144-0

To identify the antimicrobial activity of Caesalpinia sappan (C. sappan). Antimicrobial activity of C. sappan was tested with various solvent ethanol, aqueous and petroleum ether against various microorganisms (Salmonella typhi, Streptococcus faecalis, Escherichia coli, Enterobacter aerogenes, Pseudomonas aerogenosa, Staphylococcus aureus, Aspergillus niger, and Candida albican). Preliminary phytochemical analysis was also performed with the most potent ethanolic extract. Out of the selected various solvent extracts, the ethanolic extract showed maximum average zone of inhibition [(34.0±2.7) mm] against Pseudomonas aeruginosa and minimum [(6.0±0.3) mm] zone of inhibition was observed with petroleum ether extract against Escherichia coli coli. In addition, the preliminary phytochemical analyses showed the presence of steroids, tannin, phenol, saponins and flavonoids in the ethanolic extract. The ethanolic extract of C. sappan can be used as a potential antibacterial source for various infections.