Macrosolen cochinchinensis (Lour.): Anti-nociceptive and antioxidant activity

To investigate the anti-nociceptive activities of Macrosolen cochinchinensis (M. cochinchinensis) (Lour.) leaves extract at 100 and 200 mg/kg doses in mice and in vitro antioxidant potential. Acetic acid induced writhing, formalin test and tail immersion method were used to investigate anti-nocicept...

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Bibliographic Details
Published in:Asian Pacific journal of tropical biomedicine 2012-01, Vol.2 (1), p.S203-S207
Main Authors: Rahman, MM, Chowdhury, MAU, Uddin, ME, Islam, AMT, Hossain, MA
Format: Article
Language:English
Subjects:
Analgesic
Antinociceptive
Antioxidant
Macrosolen cochinchinensis
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Summary:To investigate the anti-nociceptive activities of Macrosolen cochinchinensis (M. cochinchinensis) (Lour.) leaves extract at 100 and 200 mg/kg doses in mice and in vitro antioxidant potential. Acetic acid induced writhing, formalin test and tail immersion method were used to investigate anti-nociceptive activities of methanol extract of M. cochinchinensis in mice. The in vitro antioxidant potential was determined by DPPH free radical scavenging activity and reducing power capacity. Methanol extract of M. cochinchinensis at 200 mg/kg significantly (P
ISSN:2221-1691
2588-9222
DOI:10.1016/S2221-1691(12)60160-9