Reflectance Confocal Microscopy in Lentigo Maligna

Abstract Lentigo maligna is the most common type of facial melanoma. Diagnosis is complicated, however, as it shares clinical and dermoscopic characteristics with other cutaneous lesions of the face. Reflectance confocal microscopy is an imaging technique that permits the visualization of characteri...

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Bibliographic Details
Published in:Actas dermo-sifiliográficas (English ed.) 2016-12, Vol.107 (10), p.830-835
Main Authors: Gamo, R, Pampín, A, Floristán, U
Format: Article
Language:English
Subjects:
Dermatology
Dermatoscopia
Dermoscopy
Internal Medicine
Lentigo maligna
Lentigo maligno
Microscopio confocal de reflectancia
Reflectance confocal microscopy
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Summary:Abstract Lentigo maligna is the most common type of facial melanoma. Diagnosis is complicated, however, as it shares clinical and dermoscopic characteristics with other cutaneous lesions of the face. Reflectance confocal microscopy is an imaging technique that permits the visualization of characteristic features of lentigo maligna. These include a disrupted honeycomb pattern and pagetoid cells with a tendency to show folliculotropism. These cells typically have a dendritic morphology, although they may also appear as round cells measuring over 20 μm with atypical nuclei. Poorly defined dermal papillae and atypical cells may be seen at the dermal-epidermal junction and can form bridges resembling mitochondrial structures. Other characteristic findings include junctional swelling with atypical cells located around the follicles, resembling caput medusae. Reflectance confocal microscopy is a very useful tool for diagnosing lentigo maligna.
ISSN:1578-2190
2173-5778
1578-2190
DOI:10.1016/j.adengl.2016.09.014