Platelet-Rich Plasma for the Treatment of Photodamage of the Skin of the Hands

Platelet-rich plasma (PRP) provides growth factors that stimulate fibroblast activation and induce the synthesis of collagen and other components of the extracellular matrix. The objective of this study was to evaluate the effect of PRP in the treatment of photodamage of the skin of the hands. Exper...

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Bibliographic Details
Published in:Actas dermo-sifiliográficas (English ed.) 2017-10, Vol.108 (8), p.746-751
Main Authors: Cabrera-Ramírez, J.O., Puebla-Mora, A.G., González-Ojeda, A., García-Martínez, D., Cortés-Lares, J.A., Márquez-Valdéz, A.R., Contreras-Hernández, G.I., Bracamontes-Blanco, J., Saucedo-Ortíz, J.A., Fuentes-Orozco, C.
Format: Article
Language:English
Subjects:
Adult
Biopsy
Cell Count
Collagen - analysis
Factores de crecimiento
Female
Fibroblasts - pathology
Fotodaño
Growth factors
Hand
Humans
Injections, Subcutaneous
Middle Aged
Photodamage
Plasma rico en plaquetas
Platelet-Rich Plasma
Severity of Illness Index
Skin - blood supply
Skin - chemistry
Skin - pathology
Skin - radiation effects
Skin Aging
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Summary:Platelet-rich plasma (PRP) provides growth factors that stimulate fibroblast activation and induce the synthesis of collagen and other components of the extracellular matrix. The objective of this study was to evaluate the effect of PRP in the treatment of photodamage of the skin of the hands. Experimental study enrolling persons with photoaged skin on the dorsum of the hands (Glogau photoaging scale, type III, or Fitzpatrick wrinkle classification, type II) were included between August 2012 and January 2013. A histological comparison was made of skin biopsies taken before and after the application of PRP to the skin of the dorsum of the hands. The mean (SD) age of the 18 women enrolled was 47.9 (4.3) years. Histological analysis showed an increase in the number of fibroblasts (P
ISSN:1578-2190
1578-2190
2173-5778
DOI:10.1016/j.adengl.2017.07.002