Reinforcement of an infection control bundle targeting prevention practices for Clostridioides difficile in Veterans Health Administration nursing homes

• Published in: American journal of infection control 2020-06, Vol.48 (6), p.626-632
• Main Authors: Mayer, Jeanmarie, Stone, Nimalie D., Leecaster, Molly, Hu, Nan, Pettey, Warren, Samore, Matthew, Pacheco, Susan M., Sambol, Susan, Donskey, Curtis, Jencson, Annette, Gupta, Kalpana, Strymish, Judith, Johnson, David, Woods, Christopher, Young, Edward, McDonald, L. Clifford, Gerding, Dale
• Format: Article
• Language: English
• Subjects: Implementation barriers; Implementation challenges; Long term care; Long-term care facilities
• ISSN: 0196-6553; 1527-3296
• DOI: 10.1016/j.ajic.2019.09.019

•Optimal components to include in C. difficile prevention bundles are not clear.•Infection control and antimicrobial prescribing practices vary across long term care.•Implementation of infection prevention bundles are challenging in long term care.•Simple interventions may be more effective for resource limited settings. Clostridioides difficile infection (CDI) causes significant morbidity in nursing home residents. Our aim was to describe adherence to a bundled CDI prevention initiative, which had previously been deployed nationwide in Veterans Health Administration (VA) long-term care facilities (LTCFs), and to improve compliance with reinforcement. A multicenter pre- and post-reinforcement of the VA bundle consisting of environmental management, hand hygiene, and contact precautions was conducted in 6 VA LTCFs. A campaign to reinforce VA bundle components, as well as to promote select antimicrobial stewardship recommendations and contact precautions for 30 days, was employed. Hand hygiene, antimicrobial usage, and environmental contamination, before and after bundle reinforcement, were assessed. All LTCFs reported following the guidelines for cleaning and contact precautions until diarrhea resolution pre-reinforcement. Environmental specimens rarely yielded C difficile pre- or post-reinforcement. Proper hand hygiene across all facilities did not change with reinforcement (pre 52.51%, post 52.18%), nor did antimicrobial use (pre 87–197 vs. post 84–245 antibiotic days per 1,000 resident-days). LTCFs found it challenging to maintain prolonged contact precautions. Variation in infection prevention and antimicrobial prescribing practices across LTCFs were identified and lessons learned. Introducing bundled interventions in LTCFs is challenging, given the available resources, and may be more successful with fewer components and more intensive execution with feedback.