Design considerations and animal experiment on a new bilateral mandibular distraction device

• Published in: Journal of oral and maxillofacial surgery, medicine, and pathology medicine, and pathology, 2013-07, Vol.25 (3), p.210-213
• Main Authors: Zhang, Qing-Bin, Dong, Fu-Sheng, Zhang, Zhao-Qiang, Yang, Bin
• Format: Article
• Language: English
• Subjects: Distraction osteogenesis; Distractor; Histology; Mandible; Radiography
• ISSN: 2212-5558; 2212-5566
• DOI: 10.1016/j.ajoms.2012.09.003

To investigate the efficiency of a new innovative bilateral distraction device made of titanium alloy to prolong the bilateral mandibles simultaneously on goats. Twelve adult goats were recruited and randomly divided into 4 groups. Each group was sacrificed at 1 week, 2 weeks, 3 weeks and 4 weeks after distraction period respectively. X-rays were taken and histological examination was performed. The regenerated bone was analyzed. The DO was successful in the research. The radiographs and histological results both verified new bone bridging distraction gap. X-rays showed that bone mineral density increased gradually and histological outcomes demonstrated that collagen bundles initially formed in the distraction region and were followed by calcification and osteogenesis increasingly with time going on. This study shows excellent bone formation in the distraction area, which demonstrates the applicability and positive effects of the combined bilateral mandibular distractor. It displayed merits and avoided shortcomings of both external and internal distractors. At the same time, the price was lowered to an affordable level domestically.