Parental obesity is associated with the severity of childhood obesity and its comorbidities

• Published in: Anales de Pediatría 2019-04, Vol.90 (4), p.224-231
• Main Authors: Martínez-Villanueva, Julián, González-Leal, Rocío, Argente, Jesús, Martos-Moreno, Gabriel Ángel
• Format: Article
• Language: English
• Subjects: Adolescent; Adolescente; Body Mass Index; Carbohydrate metabolism; Child; Child, Preschool; Childhood obesity; Comorbilidades metabólicas; Female; Humans; Infant; Insulin Resistance; Male; Maternal obesity; Metabolic comorbidities; Metabolic syndrome; Metabolic Syndrome - epidemiology; Metabolismo hidrocarbonado; Obesidad materna; Obesidad parental; Obesidad pediátrica; Obesity - epidemiology; Parental obesity; Parents; Pediatric Obesity - epidemiology; Retrospective Studies; Severity of Illness Index; Síndrome metabólico
• ISSN: 2341-2879; 2341-2879
• DOI: 10.1016/j.anpede.2018.06.010

The influence of parental obesity on their obese offsprings is acknowledged but insufficiently characterised. Retrospective study of 800 obese patients (45.2% girls; age: 10.35±3.40 years, body mass index [BMI]: +4.22±1.68 standard deviation score [SDS]). Group comparison according to the presence of obesity in none (n=347) or any of the parents (n=453), and then whether the obese parent was the father (n=185), the mother (n=151), or both parents (n=117) were performed. The parameters analysed were: Age at the onset of the obesity and at their first visit, birth weight (BW), BMI-SDS, blood glucose, insulin level, homeostatic model assessment (HOMA) index, total cholesterol (TC), HDL, LDL, triglycerides, 25-OH-vitamin-D, area under the curve (AUC) for insulin in the oral glucose tolerance test (OGTT), whole body insulin sensitivity index (WBISI), LDL/HDL and TC/HDL ratios, and weight loss after 12 month follow-up. No differences were observed between groups as regarding gender, ethnic background, or pubertal stage. Patients with one obese parent showed higher BW-SDS and BMI-SDS (P