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Liquid metal droplet robot

[Display omitted] •A solid core-liquid shell structured liquid metal droplet robot was introduced.•The robot can move in 3D space with the interplay of electric and magnetic fields.•The hollow core of the robot entrusts it with the unique cargo and drug delivery ability. Liquid metal (LM) droplets m...

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Published in:Applied materials today 2020-06, Vol.19, p.100597, Article 100597
Main Authors: Li, Fangxia, Shu, Jian, Zhang, Leran, Yang, Nailin, Xie, Jie, Li, Xiangpeng, Cheng, Liang, Kuang, Shaolong, Tang, Shi-Yang, Zhang, Shiwu, Li, Weihua, Sun, Lining, Sun, Dong
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cited_by cdi_FETCH-LOGICAL-c300t-80f53d7d66a17ac34e1679cf9c02c50fccefcfc906210e9dbf11da2e73ea4ef43
cites cdi_FETCH-LOGICAL-c300t-80f53d7d66a17ac34e1679cf9c02c50fccefcfc906210e9dbf11da2e73ea4ef43
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container_start_page 100597
container_title Applied materials today
container_volume 19
creator Li, Fangxia
Shu, Jian
Zhang, Leran
Yang, Nailin
Xie, Jie
Li, Xiangpeng
Cheng, Liang
Kuang, Shaolong
Tang, Shi-Yang
Zhang, Shiwu
Li, Weihua
Sun, Lining
Sun, Dong
description [Display omitted] •A solid core-liquid shell structured liquid metal droplet robot was introduced.•The robot can move in 3D space with the interplay of electric and magnetic fields.•The hollow core of the robot entrusts it with the unique cargo and drug delivery ability. Liquid metal (LM) droplets made from gallium-based alloys exhibit excellent biomimetic locomotion and deformation capabilities under external stimulating fields and have presented potentials in a variety of applications. However, its application in robotics is presently hampered by limited maneuverability in two-dimensional (2D) space and weak cargo carrying capacity. Here, we propose a composite liquid metal droplet robot (LMDR) which appears as a LM droplet but exhibits an extraordinary actuating performance in 3D space. The LMDR is fabricated by assembling a hollow and spherical-shaped magnetic internal framework (IF) into a LM droplet, and the IF can be disassembled from the LM droplet with the application of an external magnetic field. The maneuver of the LMDR is realized using the interplay of electric and magnetic fields, and complex actuation especially jumping to avoid obstacles, climbing steep slopes, and rotating its body to the desired posture can be achieved. The hollow IF within the LMDR has a cargo carrying capacity and we demonstrate a proof-of-concept experiment to show the transportation and controlled release of a chemical indicator using the LMDR. More importantly, an in vitro targeted drug delivery and therapy trial to treat breast cancer cells (4T1) with a drug loaded LMDR is also successfully performed. The demonstrated capabilities of the LMDR present a promising potential in developing future targeted drug delivery and soft robotic systems with high controllability and multi-functionalities.
doi_str_mv 10.1016/j.apmt.2020.100597
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Liquid metal (LM) droplets made from gallium-based alloys exhibit excellent biomimetic locomotion and deformation capabilities under external stimulating fields and have presented potentials in a variety of applications. However, its application in robotics is presently hampered by limited maneuverability in two-dimensional (2D) space and weak cargo carrying capacity. Here, we propose a composite liquid metal droplet robot (LMDR) which appears as a LM droplet but exhibits an extraordinary actuating performance in 3D space. The LMDR is fabricated by assembling a hollow and spherical-shaped magnetic internal framework (IF) into a LM droplet, and the IF can be disassembled from the LM droplet with the application of an external magnetic field. The maneuver of the LMDR is realized using the interplay of electric and magnetic fields, and complex actuation especially jumping to avoid obstacles, climbing steep slopes, and rotating its body to the desired posture can be achieved. 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The hollow IF within the LMDR has a cargo carrying capacity and we demonstrate a proof-of-concept experiment to show the transportation and controlled release of a chemical indicator using the LMDR. More importantly, an in vitro targeted drug delivery and therapy trial to treat breast cancer cells (4T1) with a drug loaded LMDR is also successfully performed. The demonstrated capabilities of the LMDR present a promising potential in developing future targeted drug delivery and soft robotic systems with high controllability and multi-functionalities.</abstract><pub>Elsevier Ltd</pub><doi>10.1016/j.apmt.2020.100597</doi><orcidid>https://orcid.org/0000-0002-2028-8780</orcidid><orcidid>https://orcid.org/0000-0001-5590-7943</orcidid><orcidid>https://orcid.org/0000-0002-3079-8880</orcidid><orcidid>https://orcid.org/0000-0003-3945-4037</orcidid></addata></record>
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source ScienceDirect Journals
subjects 3D actuation
EGaIn
Liquid metal
Soft robotics
Targeted drug delivery
title Liquid metal droplet robot
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