Effect of surface modification on the porous silicon infiltrated with biomolecules

• Published in: Applied surface science 2013-01, Vol.264, p.767-771
• Main Authors: Lawrence, B., Alagumanikumaran, N., Prithivikumaran, N., Jeyakumaran, N., Ramadas, V., Natarajan, B.
• Format: Article
• Language: English
• Subjects: Biofunctionalized porous silicon surface; Biosensor; Chicken blood plasma; Chicken blood serum; Condensed matter: electronic structure, electrical, magnetic, and optical properties; Condensed matter: structure, mechanical and thermal properties; Cross-disciplinary physics: materials science; rheology; Exact sciences and technology; Nanostructured porous silicon; Physics
• ISSN: 0169-4332; 1873-5584
• DOI: 10.1016/j.apsusc.2012.10.118

Porous silicon is a very host material for sensing application as it has a large internal surface cover and its optical properties can be changed by infiltrating the pores by biomolecules. The oxidized porous silicon layer was treated with chicken blood plasma and serum and the modification in the optical properties of surface layer was studied. [Display omitted] ► Nanocrystalline porous silicon was fabricated by an electrochemical etching method. ► The oxidized porous silicon was prepared by thermal treatment. ► Biomolecules (chicken blood plasma and serum) were infilterated into nanocrystalline porous silicon and their structural and optical properties were characterized. ► The infilterated biomolecules modified the optical properties of the porous silicon surface. ► Changes in the Photoluminescence emission intensity can be applied in optical biosensor. Nanostructured porous silicon was prepared by electrochemical etching method. The porous silicon has advantages over planar platforms in biosensor development due to its increased surface area. The high surface area in the porous silicon biosensors will allow for higher biosensor sensitivity while using as a smaller device. The porous silicon optical sensing device works on the basis of changes in its physical properties especially photoluminescence or reflectance, on exposure to the surrounding environment. In the present investigation, porous silicon was bio-functionalized through the deposition of functional groups on its surface by adsorption of chicken blood plasma and serum. SEM, FTIR and photoluminescence studies were carried out for bio-functionalized porous silicon surfaces to study the possibility for utilizing porous silicon as a biomaterial for biosensor applications instead of utilizing porous silicon as a biosensor and biomaterial.