A distributed parameter model for the spray drying of multicomponent droplets with a crust formation

• Published in: Advanced powder technology : the international journal of the Society of Powder Technology, Japan Japan, 2013-01, Vol.24 (1), p.324-330
• Main Authors: Gac, Jakub M., Gradoń, Leon
• Format: Article
• Language: English
• Subjects: Distributed parameter model; Drug delivery systems; Heat and mass transfer; Numerical modeling; Spray drying
• ISSN: 0921-8831; 1568-5527
• DOI: 10.1016/j.apt.2012.08.004

[Display omitted] ► A new distributed parameter model for simulations of spray-drying process. ► Simplified model to simulate a crust formation in case of multicomponent solutions. ► At some conditions of a process segregation of components in particle formed possible. ► The thickness of the layer of particle depends on crystallization kinetics. The new distributed parameter model is formulated for the purpose of the investigation of spray drying of multi-component solutions. The main feature of this model is the division of a droplet/wet particle into shells and formulating the mass and heat balances for each shell. In opposition to most similar numerical models, this one takes into account the crust formation during the second stage of drying. By means of this model, we investigate the conditions in which the segregation of the components in particle form takes place. We take into account the initial concentrations of the components in solution, its solubility and diffusion coefficients as model parameters for consideration of the different particle structures.