Synthesis, characterization and antibacterial activity of some new pyrazole based Schiff bases

In the present study a series of new Schiff bases were synthesized. All the synthesized compounds were characterized by IR, 1H NMR, mass spectral and elemental analyses. Newly synthesized compounds were screened for their antibacterial (Staphylococcus aureus, Bacillus subtilis, Escherichia coli and...

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Bibliographic Details
Published in:Arabian journal of chemistry 2013-07, Vol.6 (3), p.335-340
Main Authors: Malladi, Shridhar, Isloor, Arun M., Isloor, Shrikrishna, Akhila, D.S., Fun, Hoong-Kun
Format: Article
Language:English
Subjects:
Antimicrobial activity
Pyrazoles
Schiff bases
Triazoles
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Summary:In the present study a series of new Schiff bases were synthesized. All the synthesized compounds were characterized by IR, 1H NMR, mass spectral and elemental analyses. Newly synthesized compounds were screened for their antibacterial (Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa) activity. The results revealed that, compounds 3f and 3c have exhibited significant biological activity against the tested microorganisms.
ISSN:1878-5352
1878-5379
DOI:10.1016/j.arabjc.2011.10.009