Dependence in performing activities as a predictor of mortality following hospitalization for chronic obstructive pulmonary disease exacerbation

• Published in: Archivos de bronconeumología (English ed.) 2020-05, Vol.56 (5), p.291-297
• Main Authors: Fernández-García, Sara, Represas-Represas, Cristina, Ruano-Raviña, Alberto, Botana-Rial, Maribel, Martínez-Reglero, Cristina, Villar, Alberto Fernández
• Format: Article
• Language: English
• Subjects: COPD; Dependencia; Dependency; EPOC; Exacerbaciones; Exacerbations; Mortalidad; Mortality; Predictores; Predictors
• ISSN: 1579-2129; 1579-2129
• DOI: 10.1016/j.arbr.2020.03.004

Scant evidence is available on whether dependency for basic (BADL) or instrumental (IADL) activities of daily living can be predictors of mortality after severe COPD exacerbation (COPDE). In addition, it is as yet unclear whether the inclusion of this parameter in a multidimensional score can improve the prediction of mortality. Prospective cohort study, with follow-up of patients discharged after COPDE and multivariate analysis of clinical-demographic and dependency variables (Barthel and Lawton and Brody indices) as predictors of mortality. Three scores were generated (including or not including dependency for BADL and IADL) that were compared with each other and with other commonly used multidimensional indices (BODEx, ADO, DOSE, CODEx). In total, 247 patients were included, 112 (45%, 3); and 195 (72.4%) had some dependency for BADL and IADL. Survival was 631.7 (258.8) days, 95% confidence interval (95% CI), 60–912 days. Fifty-four (21.9%, 95% CI 17–27) patients died. Age > 60 years, FEV1