Surgical treatment of thyroid cancer: Established and novel approaches

• Published in: Baillière's best practice & research. Clinical endocrinology & metabolism 2023-01, Vol.37 (1), p.101664, Article 101664
• Main Authors: Pace-Asciak, Pia, Russell, Jonathon O., Tufano, Ralph P.
• Format: Article
• Language: English
• Subjects: radiofrequency ablation; thyroid cancer; thyroid surgery; transoral thyroidectomy
• ISSN: 1521-690X; 1878-1594
• DOI: 10.1016/j.beem.2022.101664

Thyroid surgery is one of the most common head and neck procedures. The thyroid can be accessed through an anterior cervical incision, or by remote access techniques such as the transoral endoscopic thyroidectomy vestibular approach (TOETVA) which is favored for its ease, safety and direct plane to the thyroid gland. Other novel approaches for targeting small-localized well-differentiated thyroid cancer are by thermal ablation, namely ultrasound guided radiofrequency ablation. These innovative techniques for minimizing a cutaneous scar or for targeting small cancers directly without removal of the gland have developed alongside our realization that low risk well-differentiated thyroid cancer tends to be slow growing and indolent. Up to date, the most robust data supports offering these therapies primarily to patients who would be eligible for active surveillance protocols. In this paper, we review the traditional surgical approaches for removing well-differentiated thyroid cancer, as well as innovative remote access techniques (namely TOETVA), and minimally invasive thermal ablation (namely RFA).