Enhanced production of biosurfactant by a marine bacterium on statistical screening of nutritional parameters

Marine microorganisms can serve as rich sources for novel biosurfactants with diverse biological activities. In the present investigation, the nutritional requirement for the growth and biosurfactant production by a marine bacterium was determined using a Plackett–Burman-based statistical screening...

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Bibliographic Details
Published in:Biochemical engineering journal 2008-12, Vol.42 (3), p.254-260
Main Authors: Mukherjee, Soumen, Das, Palashpriya, Sivapathasekaran, C., Sen, Ramkrishna
Format: Article
Language:English
Subjects:
Biosurfactant
Chromatography
Fermentation
Optimization
Plackett–Burman design
Submerged culture
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Summary:Marine microorganisms can serve as rich sources for novel biosurfactants with diverse biological activities. In the present investigation, the nutritional requirement for the growth and biosurfactant production by a marine bacterium was determined using a Plackett–Burman-based statistical screening procedure. Six out of the eleven factors of a reported production medium were found to be critically affecting the biosurfactant metabolism. Glucose, the carbon substrate of the medium was the most influential factor with an effect contribution of 78.13% and a very low p-value of
ISSN:1369-703X
1873-295X
DOI:10.1016/j.bej.2008.07.003